Guppi is a graduate from Oxford University where she completed an MSc in Global Health Sciences. Her interest in climate change and health started while she was a student in Leeds. She co-founded the Healthy Planet campaign and encouraged the student global health network Medsin to take further action on the issue. She worked in the Health and Education Campaigns team in Oxfam, as well as working closely with the Global Climate Campaigns team in the run up to Copenhagen. She also helped start up the UK Youth Climate Coalition,